About PhyreRisk

PhyreRisk is a dynamic web application developed to enable the exploration and mapping of genetic variants onto experimental and predicted structures of proteins and protein complexes. PhyreRisk integrates data from several public domain and in-house databases with information about diseases, genetic variation, biological pathways and protein structure and then facilitate the informed analysis by a wide community of users throughout the world.

PhyreRisk is funded by The Wellcome Trust. Production of Phyre structures is funded by the BBSRC.

Core Team Members

PhyreRisk is developed at Imperial college London by the Structural Bioinfomatics Group headed by Professor Michael J E Sternberg.


Tochukwu (Charles) Ofoegbu

Lead Software Developer (PhyreRisk)

Lawrence A Kelley

Coordinator & Developer (Phyre Server)

Alessia David

Clinical Research Fellow and Honorary Lecturer

Professor Michael J E Sternberg

Head of Group and Director of Centre for Bioinformatics

Credits

People who have collaborated with the team and/or contributed code.


Stefans Mezilus

Phyre3 co-developer

Sophia Marsmann

MSc. Student of Bioinformatics (2018)

Developed Prototype for VEP integration

Leonie Stroemich

MSc. Student of Bioinformatics (2018)

Developed Prototype for VEP integration