Sequence Browser (O43291-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
252

Isoforms (From UniProt)

Isoform
Remark
Ref
O43291-2
No experimental confirmation available.
VSP_043680
O43291-1  
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Variants (From UniProt)

Type
Variation
Position
sequence variant
Y → C
163
sequence conflict
Q → H
3
sequence conflict
R → K
53
splice variant
Missing
36 - 92
sequence variant
V → L
200
sequence conflict
R → P
11
sequence conflict
D → H
240

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
Kunitz-type protease inhibitor 2
Other Names:
Hepatocyte growth factor activator inhibitor type 2, Placental bikunin
Primary Accession:
O43291
Other Accessions:
A8K667, B4DLU1, O00271, O14895, Q5TZQ3, Q969E0
Gene :
SPINT2*, synonyms (HAI2, KOP)
Organism :
Human
Entry Name :
SPIT2_HUMAN
Length :
252
Mass (Da) :
28,228
Last modified :
21-Jan-2001
Version :
v2
Isoforms :
2 
Variants :
7 
Interactions :
0 
Structures :
Experimental 1 | Phyre prediction 1
Function : Show Hide

Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.

Interactions (From UniProt)

No interactions reported for this protein.