Sequence Browser (O94822-2)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
1766

Isoforms (From UniProt)

Isoform
Remark
Ref
O94822-1
O94822-3
No experimental confirmation available.
VSP_044911
O94822-2  
VSP_040138
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Protein Information (From UniProt)

Protein:
E3 ubiquitin-protein ligase listerin
Other Names:
RING finger protein 160, RING-type E3 ubiquitin transferase listerin, Zinc finger protein 294
Primary Accession:
O94822
Other Accessions:
A6NL41, A7E2D0, B2RTS0, C9J7U3, J3KPL4, Q05C47, Q9H8M4, Q9NUY5, Q9P0E9
Gene :
LTN1*, synonyms (C21orf10, C21orf98, KIAA0714, RNF160, ZNF294)
Organism :
Human
Entry Name :
LTN1_HUMAN
Length :
1,766
Mass (Da) :
200,552
Last modified :
30-Jan-2010
Version :
v6
Isoforms :
3 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity).