Sequence Browser (P17693-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
338

Isoforms (From UniProt)

Isoform
Remark
Ref
P17693-3
VSP_059191
P17693-6
VSP_059192 VSP_059195 VSP_059197
P17693-1  
P17693-2
VSP_059192 VSP_059195
P17693-4
VSP_059196
P17693-5
VSP_059197
P17693-7
VSP_059193 VSP_059194
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
splice variant
Missing
115 - 206
splice variant
Missing
117 - 338
splice variant
D → K
207
mutagenesis site
C → S
66
splice variant
Missing
115 - 298
splice variant
S → E
116
splice variant
Missing
207 - 298
splice variant
KQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD → SKEGDGGIMSVRESRSLSEDL
299 - 338

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
HLA class I histocompatibility antigen, alpha chain G
Other Names:
HLA G antigen, MHC class I antigen G
Primary Accession:
P17693
Other Accessions:
Gene :
HLA-G*, synonyms (HLA-6.0, HLAG)
Organism :
Human
Entry Name :
HLAG_HUMAN
Length :
338
Mass (Da) :
38,224
Last modified :
01-Jan-1990
Version :
v1
Isoforms :
7 
Variants :
8 
Interactions :
3 
Structures :
Experimental 8 | Phyre prediction 2
Function : Show Hide

Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.

Interactions (From UniProt)

With
Entry
IntAct
Exp
LILRB1
Q8NHL6
EBI-1043063, EBI-2805262
8
Itself
EBI-1043063, EBI-1043063
5
LILRB2
Q8N423
EBI-1043063, EBI-2816428
10