Sequence Browser (P22307-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
547

Isoforms (From UniProt)

Isoform
Remark
Ref
P22307-1  
P22307-3
VSP_042686 VSP_042687
P22307-4
Produced by alternative splicing. No experimental confirmation available.
VSP_045187
P22307-7
Produced by alternative splicing.
VSP_042686
P22307-8
Produced by alternative splicing.
VSP_047267
P22307-2
Contains a mitochondrial transit peptide at positions 1-20.
VSP_018977
P22307-5
VSP_018977 VSP_047269 VSP_047270
P22307-6
VSP_018977 VSP_047268
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
splice variant
Missing
1 - 81
splice variant
Missing
67 - 110
splice variant
Missing
412 - 414
splice variant
Missing
464 - 547
mutagenesis site
N → D
528
mutagenesis site
G → D
530
sequence conflict
A → V
56
sequence conflict
K → Q
341
sequence conflict
A → D
472
sequence conflict
D → A
501
splice variant
Missing
1 - 404
splice variant
Missing
43 - 66
splice variant
LAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQLQPGNAKL → GHSCS
362 - 547
splice variant
EGEQFVKKIGGIFAFKV → IRRLTAQSQWLTQTSWL
447 - 463
sequence variant
A → D
155
mutagenesis site
N → I
528
sequence conflict
T → A
10
sequence conflict
V → A
116
sequence conflict
G → D
393
sequence conflict
K → Q
482
sequence conflict
K → P
522

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
Non-specific lipid-transfer protein
Other Names:
Propanoyl-CoA C-acyltransferase, SCP-chi, SCPX, Sterol carrier protein 2, Sterol carrier protein X
Primary Accession:
P22307
Other Accessions:
A6NM69, B4DGJ9, B4DHP6, C9JC79, D3DQ37, E1B6W5, F2Z3J1, Q15432, Q16622, Q5VVZ1, Q6NXF4, Q99430
Gene :
SCP2*
Organism :
Human
Entry Name :
NLTP_HUMAN
Length :
547
Mass (Da) :
58,994
Last modified :
01-Jan-1997
Version :
v2
Isoforms :
8 
Variants :
21 
Interactions :
3 
Structures :
Experimental 2 | Phyre prediction 4
Function : Show Hide

Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.

Interactions (From UniProt)

With
Entry
IntAct
Exp
Cav1
P49817
EBI-1050999, EBI-1161338
3
CAV1
Q03135
EBI-1050999, EBI-603614
3
TRIP13
Q15645
EBI-1050999, EBI-358993
4