Sequence Browser (P28476-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
465

Isoforms (From UniProt)

Isoform
Remark
Ref
P28476-1  
P28476-2
Isoform 2 could be translated from an upstream initiator ATG located in frame within the first coding exon. The probability of a signal peptide within this isoform is very low. No experimental confirmation available.
VSP_044373
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Variants (From UniProt)

Type
Variation
Position
sequence conflict
Y → H
209
splice variant
M → MVKPGGICSATGYWKAAFCLTDVHKM
1

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
Gamma-aminobutyric acid receptor subunit rho-2
Other Names:
GABA(A) receptor subunit rho-2, GABA(C) receptor
Primary Accession:
P28476
Other Accessions:
A2BDE4, Q9H153
Gene :
GABRR2*
Organism :
Human
Entry Name :
GBRR2_HUMAN
Length :
465
Mass (Da) :
54,151
Last modified :
31-Jan-2012
Version :
v5
Isoforms :
2 
Variants :
2 
Interactions :
0 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission.

Interactions (From UniProt)

No interactions reported for this protein.