Sequence Browser (P48643-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
541

Isoforms (From UniProt)

Isoform
Remark
Ref
P48643-2
No experimental confirmation available.
VSP_054005 VSP_054006
P48643-1  
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Variants (From UniProt)

Type
Variation
Position
splice variant
Missing
56 - 110
sequence variant
H → R
147
sequence conflict
G → D
512
splice variant
Missing
1 - 38
sequence variant
E → V
146
sequence conflict
N → D
55

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
T-complex protein 1 subunit epsilon
Other Names:
CCT-epsilon
Primary Accession:
P48643
Other Accessions:
A8JZY8, A8K2X8, B4DYD8
Gene :
CCT5*, synonyms (CCTE, KIAA0098)
Organism :
Human
Entry Name :
TCPE_HUMAN
Length :
541
Mass (Da) :
59,671
Last modified :
01-Jan-1996
Version :
v1
Isoforms :
2 
Variants :
6 
Interactions :
1 
Structures :
Experimental 2 | Phyre prediction 1
Function : Show Hide

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

Interactions (From UniProt)

With
Entry
IntAct
Exp
SSSCA1
O60232
EBI-355710, EBI-741415
3