Sequence Browser (Q15438-2)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
398

Isoforms (From UniProt)

Isoform
Remark
Ref
Q15438-1
Q15438-3
No experimental confirmation available.
VSP_055884
Q15438-2  
VSP_006034
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3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
Cytohesin-1
Other Names:
PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1
Primary Accession:
Q15438
Other Accessions:
A6NFW7, B7Z1T4, Q9P123, Q9P124
Gene :
CYTH1*, synonyms (D17S811E, PSCD1)
Organism :
Human
Entry Name :
CYH1_HUMAN
Length :
398
Mass (Da) :
46,413
Last modified :
01-Jan-1996
Version :
v1
Isoforms :
3 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.