Sequence Browser (Q9UKP5-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
1117

Isoforms (From UniProt)

Isoform
Remark
Ref
Q9UKP5-1  
Q9UKP5-3
VSP_037096 VSP_037097
Q9UKP5-2
Contains critical point mutations in the region encoding the catalytic domain as well as 2 point mutations compared with genomic sequence. May either be a rare polymorphism or may have arisen through a combination of aberrant RNA editing and point mutation/sequencing error.
VSP_037095 VSP_037098 VSP_037099
Q9UKP5-4
VSP_037093 VSP_037094
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
splice variant
Missing
293 - 1117
splice variant
DSGRGTCLDNEP → EFLKLGDSISGS
457 - 468
splice variant
VQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCPPEWFIGDW → KMPTRQPTQRARWRTKHILSYALCLLKKLIGNISCRFASSCNLAKETLL
860 - 908
sequence conflict
L → S
4
sequence conflict
S → P
83
sequence conflict
G → V
406
sequence conflict
PA → LK
588 - 589
splice variant
AKLYRDSSLG → RLPNFTVIPA
283 - 292
splice variant
TKGHEAAKLMAAHITANTNPFSWSACSRDYITSFLDSGRGTCLDNEPPKRDFLYPAVAPGQVYDADEQCRFQYGATSRQCKYG → RKVMKQQNYGSSHYCEYQSFFLVCLQSRFHHQLFR
422 - 504
splice variant
Missing
469 - 1117
splice variant
Missing
909 - 1117
sequence conflict
D → G
24
sequence conflict
Y → H
229
sequence conflict
E → G
426
sequence conflict
D → G
712

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
A disintegrin and metalloproteinase with thrombospondin motifs 6
Primary Accession:
Q9UKP5
Other Accessions:
Q59EX6, Q5IR87, Q5IR88, Q5IR89, Q68DL1
Gene :
ADAMTS6*
Organism :
Human
Entry Name :
ATS6_HUMAN
Length :
1,117
Mass (Da) :
125,273
Last modified :
05-Jan-2009
Version :
v2
Isoforms :
4 
Variants :
15 
Interactions :
0 
Structures :
Experimental 0 | Phyre prediction 5
Function : Show Hide

Interactions (From UniProt)

No interactions reported for this protein.