3D Structure Display
By clicking on any PDB entry under the 'Available Structures' section, you can visualise in this panel, the 3D details about the protein, and also see information about it's interactions and mutations where available.
To analyse the structural impact of your missense variant:
- Select the corresponding experimental/modelled structure from the "Available Structures" Panel.
- Right-click on the target structure and download it.
- Go to our web server Missense3D to analyse structural impact.
Go to Missense3D
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.