Sequence Browser (Q96AW1-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
If the whole structure is coloured grey in '3D Structure Viewer' panel, please click the icon - on the top left corner of the viewer.
(If nothing changes then 'Sequence ↔ Structure' mapping may be unavailable).
1
172

Isoforms (From UniProt)

Isoform
Remark
Ref
Q96AW1-2
No experimental confirmation available.
VSP_043868
Q96AW1-4
Gene prediction based on EST data.
VSP_055723
Q96AW1-1  
Q96AW1-3
No experimental confirmation available.
VSP_043867
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
splice variant
MRRQPAKVAALLLGLLLE → M
1 - 18
splice variant
QPAKVAALLLGLLLE → TGSHAQ
4 - 18
sequence conflict
A → T
111
splice variant
RRQPAKVAALLLGLLLE → LSETLGYLSSVLLQ
2 - 18
sequence conflict
E → K
92
sequence conflict
M → T
134

3D Structure Viewer - JSMol  

3D Structure Display

By clicking on any PDB entry under the 'Available Structures' section, you can visualise in this panel, the 3D details about the protein, and also see information about it's interactions and mutations where available.

To analyse the structural impact of your missense variant:

  • Select the corresponding experimental/modelled structure from the "Available Structures" Panel.
  • Right-click on the target structure and download it.
  • Go to our web server Missense3D to analyse structural impact.

    • Go to Missense3D

Protein Information (From UniProt)

Protein:
Vesicular, overexpressed in cancer, prosurvival protein 1
Other Names:
EGFR-coamplified and overexpressed protein, Glioblastoma-amplified secreted protein, Putative NF-kappa-B-activating protein 055N
Primary Accession:
Q96AW1
Other Accessions:
B0AZU1, B2RAT4, B3KS72, C9JWR3, Q6FIE3, Q8NBN8, Q96RE5, Q9H0W4
Gene :
VOPP1*, synonyms (ECOP, GASP)
Organism :
Human
Entry Name :
VOPP1_HUMAN
Length :
172
Mass (Da) :
19,224
Last modified :
01-Jan-2001
Version :
v1
Isoforms :
4 
Variants :
6 
Interactions :
0 
Structures :
Experimental 0 | Phyre prediction 0
Function : Show Hide

Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.

Interactions (From UniProt)

No interactions reported for this protein.