3D Structure Display
By clicking on any PDB entry under the 'Available Structures' section, you can visualise in this panel, the 3D details about the protein, and also see information about it's interactions and mutations where available.
To analyse the structural impact of your missense variant:
- Select the corresponding experimental/modelled structure from the "Available Structures" Panel.
- Right-click on the target structure and download it.
- Go to our web server Missense3D to analyse structural impact.
Go to Missense3D
May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.