Sequence Browser (P01111-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
If the whole structure is coloured grey in '3D Structure Viewer' panel, please click the icon - on the top left corner of the viewer.
(If nothing changes then 'Sequence ↔ Structure' mapping may be unavailable).
1
189

Isoforms (From UniProt)

Isoform
Remark
Ref
P01111-1  
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
sequence variant
G → C
12
sequence variant
G → D
13
sequence variant
P → L
34
sequence variant
G → E
60
sequence variant
Q → R
61
mutagenesis site
C → S
181
sequence variant
G → D
12
sequence variant
G → R
13
sequence variant
T → I
50
sequence variant
Q → K
61
mutagenesis site
R → A
164

3D Structure Viewer - JSMol  

To analyse the structural impact of your missense variant:

  • Select the corresponding experimental/modelled structure from the "Available Structures" Panel.
  • Right-click on the target structure and download it.
  • Go to our web server Missense3D to analyse structural impact.

    • Go to Missense3D

Protein Information (From UniProt)

Protein:
GTPase NRas
Other Names:
Transforming protein N-Ras
Primary Accession:
P01111
Other Accessions:
Q14971, Q15104, Q15282
Gene :
NRAS*, synonyms (HRAS1)
Organism :
Human
Entry Name :
RASN_HUMAN
Length :
189
Mass (Da) :
21,229
Last modified :
21-Jan-1986
Version :
v1
Isoforms :
1 
Variants :
11 
Interactions :
5 
Structures :
Experimental 3 | Phyre prediction 2
Function : Show Hide

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

Interactions (From UniProt)

With
Entry
IntAct
Exp
Braf
P28028
EBI-721993, EBI-2584830
2
Raf1
Q99N57
EBI-721993, EBI-397757
2
BRAF
P15056
EBI-721993, EBI-365980
3
RAF1
P04049
EBI-721993, EBI-365996
3
RIN1
Q13671
EBI-721993, EBI-366017
4