Sequence Browser (P45379-1)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
298
Isoform
Remark
Ref
VSP_006643
VSP_006645 VSP_006646 VSP_006648
VSP_006648
P45379-1  
VSP_006644
VSP_006644 VSP_006645
VSP_006647
VSP_006641
VSP_006646
No experimental confirmation available.
VSP_006643 VSP_006648
VSP_006645
VSP_006642
Click on Isoform of interest to be redirected to the corresponding page
Type
Variation
Position
splice variant
Missing
18 - 32
splice variant
Missing
23 - 32
splice variant
Missing
18 - 22
splice variant
Missing
23
splice variant
Missing
99 - 137
splice variant
Missing
201
sequence variant
F → L
80
sequence variant
R → L
102
sequence variant
R → W
102
sequence variant
A → V
114
sequence variant
F → V
120
sequence variant
R → C
140
sequence variant
R → W
141
sequence variant
Missing
170
sequence variant
S → F
189
sequence variant
R → L
215
sequence variant
I → T
221
sequence variant
S → T
249
sequence variant
K → R
263
sequence variant
N → I
281
sequence variant
R → P
288
sequence conflict
K → E
242
splice variant
Missing
54
splice variant
Missing
201 - 203
sequence variant
A → V
38
sequence variant
I → N
89
sequence variant
R → Q
102
sequence variant
R → L
104
sequence variant
F → I
120
sequence variant
R → K
139
sequence variant
R → K
140
sequence variant
R → W
151
sequence variant
E → K
173
sequence variant
Missing
210
sequence variant
Missing
220
sequence variant
I → T
231
sequence variant
E → D
254
sequence variant
N → Y
279
sequence variant
R → C
288
sequence variant
R → C
296

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Protein:
Other Names:
Cardiac muscle troponin T
Primary Accession:
Other Accessions:
A2TDB9, A8K3K6, O60214, Q99596, Q99597, Q9BUF6, Q9UM96
Gene :
TNNT2*
Organism :
Human
Entry Name :
Length :
298
Mass (Da) :
35,924
Last modified :
23-Jan-2007
Version :
v3
Isoforms :
12 
Variants :
40 
Interactions :
1 
Structures :
Experimental 3 | Phyre prediction 3

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

With
Entry
IntAct
Exp
MORF4L2
Q15014
EBI-8485957, EBI-399257
3