Sequence Browser (Q96BI1-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
424

Isoforms (From UniProt)

Isoform
Remark
Ref
Q96BI1-1  
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
sequence variant
A → T
6
sequence variant
R → C
86
sequence variant
R → Q
309
sequence conflict
D → N
84
sequence conflict
A → G
230
sequence conflict
Q → K
275
sequence conflict
R → G
309
sequence variant
R → Q
12
sequence variant
S → F
233
sequence variant
W → C
324
sequence conflict
D → E
227
sequence conflict
R → K
242
sequence conflict
L → M
307

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
Solute carrier family 22 member 18
Other Names:
Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein, Efflux transporter-like protein, Imprinted multi-membrane-spanning polyspecific transporter-related protein 1, Organic cation transporter-like protein 2, Solute carrier family 22 member 1-like, Tumor-suppressing STF cDNA 5 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein, p45-Beckwith-Wiedemann region 1 A
Primary Accession:
Q96BI1
Other Accessions:
O14906, O43562, O60485, O60680, Q7LDS5, Q7LGF7
Gene :
SLC22A18*, synonyms (BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5)
Organism :
Human
Entry Name :
S22AI_HUMAN
Length :
424
Mass (Da) :
44,846
Last modified :
26-Jan-2009
Version :
v3
Isoforms :
1 
Variants :
13 
Interactions :
1 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney.

Interactions (From UniProt)

With
Entry
IntAct
Exp
NKX3-1
Q99801
EBI-11721845, EBI-1385894
4