Sequence Browser (O43653-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
If the whole structure is coloured grey in '3D Structure Viewer' panel, please click the icon - on the top left corner of the viewer.
(If nothing changes then 'Sequence ↔ Structure' mapping may be unavailable).
1
123

Isoforms (From UniProt)

Isoform
Remark
Ref
O43653-1  
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
sequence variant
E → K
39
sequence conflict
M → T
1

3D Structure Viewer - JSMol  

To analyse the structural impact of your missense variant:

  • Select the corresponding experimental/modelled structure from the "Available Structures" Panel.
  • Right-click on the target structure and download it.
  • Go to our web server Missense3D to analyse structural impact.

    • Go to Missense3D

Protein Information (From UniProt)

Protein:
Prostate stem cell antigen
Primary Accession:
O43653
Other Accessions:
Q6UW92
Gene :
PSCA*
Organism :
Human
Entry Name :
PSCA_HUMAN
Length :
123
Mass (Da) :
12,912
Last modified :
01-Jan-1998
Version :
v1
Isoforms :
1 
Variants :
2 
Interactions :
0 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.

May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

Interactions (From UniProt)

No interactions reported for this protein.