PhyreRisk ::

Sequence Browser (Q15032-1)

sequence info goes here

Available Structures (Graph-View Mode)

UniProt (Ref Seq)

Displayed Structure

Experimental Tertiary/Complex (PDB:XRay/EM)

Experimental Tertiary/Complex (PDB:NMR)

Modelled Tertiary (Phyre)

If the whole structure is coloured grey in '3D Structure Viewer' panel, please click the icon - on the top left corner of the viewer.
(If nothing changes then 'Sequence ↔ Structure' mapping may be unavailable).

1099

To download any of the 3D structure coordinate files, right click on it → select 'Download Structure [xxx]'.

Isoforms (From UniProt)

Isoform

Remark

Ref

Q15032-1

Q15032-2

VSP_017344 VSP_017345 VSP_054310

Q15032-3

VSP_054310

Q15032-4

No experimental confirmation available.

VSP_054308 VSP_054309 VSP_054310

Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type

Variation

Position

splice variant

MRMSDTVTVKDETATMKDLEAEVKDTTRVENLIKSENYGKILVE → MGLLLPDYRWFTTVDILADNCEKEPWIILFYFCGTPQSQIQRTH

1 - 44

splice variant

Missing

57 - 100

splice variant

Q → QQ

541

sequence variant

Q → P

632

sequence conflict

K → R

902

splice variant

Missing

45 - 100

splice variant

Missing

406 - 490

sequence variant

M → V

270

sequence conflict

K → E

125

sequence conflict

S → L

1075

3D Structure Viewer - JSMol

3D Structure Information placeholder

To analyse the structural impact of your missense variant:

Select the corresponding experimental/modelled structure from the "Available Structures" Panel.
Right-click on the target structure and download it.
Go to our web server Missense3D to analyse structural impact.

Go to Missense3D