Sequence Browser (Q8WTR7-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
871

Isoforms (From UniProt)

Isoform
Remark
Ref
Q8WTR7-1  
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
sequence variant
S → G
59
sequence variant
T → M
164
sequence variant
T → I
654
sequence conflict
P → A
486
sequence variant
S → G
74
sequence variant
E → G
309
sequence variant
S → A
662
sequence conflict
V → M
588

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
Zinc finger protein 473
Other Names:
Zinc finger protein 100 homolog
Primary Accession:
Q8WTR7
Other Accessions:
A8K8T7, Q9ULS9, Q9Y4Q7
Gene :
ZNF473*, synonyms (KIAA1141, ZFP100)
Organism :
Human
Entry Name :
ZN473_HUMAN
Length :
871
Mass (Da) :
100,182
Last modified :
01-Jan-2002
Version :
v1
Isoforms :
1 
Variants :
8 
Interactions :
13 
Structures :
Experimental 14 | Phyre prediction 3
Function : Show Hide

Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.

Interactions (From UniProt)

With
Entry
IntAct
Exp
AEN
Q8WTP8
EBI-751409, EBI-8637627
3
DHX57
Q6P158
EBI-751409, EBI-1051531
3
KRTAP10-8
P60410
EBI-751409, EBI-10171774
5
PRPF31
Q8WWY3
EBI-751409, EBI-1567797
3
RNPS1
D3DU92
EBI-751409, EBI-10176640
3
ZNF250
P15622-3
EBI-751409, EBI-10177272
3
ZSCAN12
O43309
EBI-751409, EBI-1210440
3
CLK2
P49760
EBI-751409, EBI-750020
3
GPATCH2L
Q9NWQ4
EBI-751409, EBI-5666657
3
KRTAP10-9
P60411
EBI-751409, EBI-10172052
3
RBM10
P98175
EBI-751409, EBI-721525
3
TRIM41
Q8WV44
EBI-751409, EBI-725997
3
ZNF792
Q3KQV3
EBI-751409, EBI-10240849
3