Sequence Browser (Q9Y4Z2-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
214

Isoforms (From UniProt)

Isoform
Remark
Ref
Q9Y4Z2-1  
Click on Isoform of interest to be redirected to the corresponding page

Variants (From UniProt)

Type
Variation
Position
sequence variant
R → S
107
sequence conflict
R → P
43
sequence conflict
S → P
165
sequence variant
R → L
93
sequence variant
F → S
199
sequence conflict
N → D
98

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
Neurogenin-3
Other Names:
Class A basic helix-loop-helix protein 7, Protein atonal homolog 5
Primary Accession:
Q9Y4Z2
Other Accessions:
Q5VVI0, Q6DJX6, Q9BY24
Gene :
NEUROG3*, synonyms (ATOH5, BHLHA7, NGN3)
Organism :
Human
Entry Name :
NGN3_HUMAN
Length :
214
Mass (Da) :
23,077
Last modified :
05-Jan-2009
Version :
v2
Isoforms :
1 
Variants :
6 
Interactions :
3 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity).

Interactions (From UniProt)

With
Entry
IntAct
Exp
TCF12
Q99081
EBI-10328570, EBI-722877
3
REL
Q04864
EBI-10328570, EBI-307352
3
TCF12
Q99081-3
EBI-10328570, EBI-11952764
5