Sequence Browser (P56159-1)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
465

Isoforms (From UniProt)

Isoform
Remark
Ref
P56159-1  
P56159-2
May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
VSP_001660
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Variants (From UniProt)

Type
Variation
Position
splice variant
Missing
140 - 144
sequence variant
T → A
366
sequence conflict
Missing
245
sequence variant
Y → N
85
sequence variant
L → R
371
sequence conflict
F → P
358

3D Structure Viewer - JSMol  

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Protein Information (From UniProt)

Protein:
GDNF family receptor alpha-1
Other Names:
RET ligand 1, TGF-beta-related neurotrophic factor receptor 1
Primary Accession:
P56159
Other Accessions:
A8KA21, O15507, O43912
Gene :
GFRA1*, synonyms (GDNFRA, RETL1, TRNR1)
Organism :
Human
Entry Name :
GFRA1_HUMAN
Length :
465
Mass (Da) :
51,456
Last modified :
23-Jan-2002
Version :
v2
Isoforms :
2 
Variants :
6 
Interactions :
0 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).

Interactions (From UniProt)

No interactions reported for this protein.