Sequence Browser (P56159-2)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
If the whole structure is coloured grey in '3D Structure Viewer' panel, please click the icon - on the top left corner of the viewer.
(If nothing changes then 'Sequence ↔ Structure' mapping may be unavailable).
1
465

Isoforms (From UniProt)

Isoform
Remark
Ref
P56159-1
P56159-2  
May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
VSP_001660
Click on Isoform of interest to be redirected to the corresponding page

3D Structure Viewer - JSMol  

To analyse the structural impact of your missense variant:

  • Select the corresponding experimental/modelled structure from the "Available Structures" Panel.
  • Right-click on the target structure and download it.
  • Go to our web server Missense3D to analyse structural impact.

    • Go to Missense3D

Protein Information (From UniProt)

Protein:
GDNF family receptor alpha-1
Other Names:
RET ligand 1, TGF-beta-related neurotrophic factor receptor 1
Primary Accession:
P56159
Other Accessions:
A8KA21, O15507, O43912
Gene :
GFRA1*, synonyms (GDNFRA, RETL1, TRNR1)
Organism :
Human
Entry Name :
GFRA1_HUMAN
Length :
465
Mass (Da) :
51,456
Last modified :
23-Jan-2002
Version :
v2
Isoforms :
2 
Structures :
Experimental 0 | Phyre prediction 2
Function : Show Hide

Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).