Sequence Browser (Q86UL8-2)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
1455

Isoforms (From UniProt)

Isoform
Remark
Ref
Q86UL8-1
Q86UL8-2  
VSP_008435
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Protein Information (From UniProt)

Protein:
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Other Names:
Atrophin-1-interacting protein 1, Atrophin-1-interacting protein A, Membrane-associated guanylate kinase inverted 2
Primary Accession:
Q86UL8
Other Accessions:
A4D1C1, A7E2C3, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1
Gene :
MAGI2*, synonyms (ACVRINP1, AIP1, KIAA0705)
Organism :
Human
Entry Name :
MAGI2_HUMAN
Length :
1,455
Mass (Da) :
158,754
Last modified :
07-Jan-2006
Version :
v3
Isoforms :
2 
Structures :
Experimental 0 | Phyre prediction 8
Function : Show Hide

Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.