Sequence Browser (Q9BXH1-2)

Available Structures (Graph-View Mode)

UniProt (Ref Seq)
Displayed Structure
Experimental Tertiary/Complex (PDB:XRay/EM)
Experimental Tertiary/Complex (PDB:NMR)
Modelled Tertiary (Phyre)
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1
193

Isoforms (From UniProt)

Isoform
Remark
Ref
Q96PG8-2
Q9BXH1-1
Q96PG8-1
Q9BXH1-2  
VSP_012238
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3D Structure Viewer - JSMol  

3D Structure Display

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Protein Information (From UniProt)

Protein:
Bcl-2-binding component 3
Other Names:
JFY-1, p53 up-regulated modulator of apoptosis
Primary Accession:
Q9BXH1
Other Accessions:
B9EGI3, O00171, Q96PG9
Gene :
BBC3*, synonyms (PUMA)
Organism :
Human
Entry Name :
BBC3_HUMAN
Length :
193
Mass (Da) :
20,532
Last modified :
01-Jan-2001
Version :
v1
Isoforms :
4 
Structures :
Experimental 0 | Phyre prediction 0
Function : Show Hide

Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.