Release History
Date Version
17-07-2019 * 1.0.1-release
11-03-2019 1.0.0-release
01-11-2018 0.2.0-release
01-10-2017 0.1.0-release
view all release history

Release Version: 0.2.0 (beta)

Release Information:
  • Version - 0.2.0 (beta)
  • Release date - 01-11-2018
  • Ability to search PhyreRisk database using UniProt accession, protein name, gene name and disease name
  • Addition of experimentally derived structures of human proteins from ePDB at EBI
  • Integration of three molecular viewers (JSMol, 3DMol, NGLViewer)
  • Integration of SIFTS resource provided by EBI to enable mapping and linking of sequence from UniProt with structure coordinates from PDB
  • Integration of VEP rest service
  • Provided ability to input custom variant using genomic coordinates (human build GRCh37 or GRCh38)
  • Provided ability to add custom variants using protoemic coordinates

Improvements / Issues Resolved:
  • Updated PhyreRisk database with 20,349 reviewed human proteins from UniProt (Nov 2018)
  • Resolved bug that prevents JSMol from loading PDB coordinate files containing disulphide bonds (SSBOND)
  • Added google map and address on contact page
  • Resolved bug preventing search on the protein page

Known Issues:
  • 3DMol viewer does not load compressed structure coordinate file - experimental structure from PDB are downloaded in a compressed format for performance and efficiency